Genizer NanoTechnology

  Cell Disruption with High Pressure Homogenizer Cell disruption is a crucial process in biotechnology, pharmaceutical research, and life sciences. Efficiently breaking open cells allows researchers to extract valuable intracellular components, including proteins, enzymes, nucleic acids, and viral vectors. One of the most reliable and scalable tools for this purpose is a high pressure homogenizer. NanoGenizer offers advanced solutions that combine precision, reproducibility, and thermal control. For more on the high pressure microfluidization homogenization technology, see our article:  High Pressure Homogenizer Introduction   How NanoGenizer High Pressure Homogenizer Achieves Cell Disruption The NanoGenizer high pressure homogenizer operates by forcing a cell suspension through diamond interaction chambers under high pressure. This generates controlled shear, impact, and cavitation forces that rupture cell membranes while preserving delicate intracellular contents. ...

  Liposomes are artificially synthesized vesicles composed of phospholipids and cholesterol that mimic biological cell membranes. Their particle sizes typically range from 50–200 nm and can be adjusted according to preparation methods. Liposomes can encapsulate both hydrophilic and hydrophobic compounds and are widely studied for drug delivery, gene delivery, and vaccine formulation research. In pharmaceutical research, lipid nanoparticles (LNPs) represent a broader class of lipid-based delivery systems, within which liposomes are a well-established and extensively characterized subclass. Precise control of particle size and distribution is critical in both liposome preparation and lipid nanoparticle production, as these parameters directly influence formulation stability, reproducibility, and in vivo performance. Phospholipid bilayer liposomes for gene delivery As liposome- and LNP-based formulations continue to expand in clinical and commercial applications, they are often catego...