Genizer NanoTechnology

  Liposomes are artificially synthesized vesicles composed of phospholipids and cholesterol that mimic biological cell membranes. Their particle sizes typically range from 50–200 nm and can be adjusted according to preparation methods. Liposomes can encapsulate both hydrophilic and hydrophobic compounds and are widely studied for drug delivery, gene delivery, and vaccine formulation research. In pharmaceutical research, lipid nanoparticles (LNPs) represent a broader class of lipid-based delivery systems, within which liposomes are a well-established and extensively characterized subclass. Precise control of particle size and distribution is critical in both liposome preparation and lipid nanoparticle production, as these parameters directly influence formulation stability, reproducibility, and in vivo performance. Phospholipid bilayer liposomes for gene delivery As liposome- and LNP-based formulations continue to expand in clinical and commercial applications, they are often catego...

 What Is Graphene and Its Applications Graphene is a two-dimensional carbon material valued for its excellent electrical conductivity, mechanical strength, thermal stability, and chemical resistance. These properties make graphene ideal for energy storage, electronics, functional coatings, conductive inks, and advanced composite materials. Challenges in Graphene Production  Graphene tends to agglomerate due to strong van der Waals forces, forming clusters that reduce its effectiveness. Traditional dispersion methods such as high-shear mixers, ball mills, bead mills, and ultrasonic dispersers often struggle to balance efficiency, precision, and batch consistency. Common limitations include broad particle size distribution, limited layer control, contamination risk, high energy use, and difficulties in scaling up. Graphene Exfoliation using NanoGenizer High Pressure Homogenizer Liquid-Phase Exfoliation with High Pressure Homogenizers High pressure homogenizers offer a reliable w...

  Creating stable and effective liquid formulations in biotechnology and pharmaceuticals hinges on achieving a uniform dispersion of active ingredients. The   Genizer NanoMixer Microfluidic Mixing System   is designed to meet this critical need, offering a compact, programmable, and highly precise solution for laboratory-scale preparation of sensitive nano-formulations. Unlike traditional methods that rely on compressed air or hydraulic oil, this electrically driven benchtop instrument gives researchers unparalleled control over the mixing process, making it an indispensable tool for developing next-generation treatments and products  . Key Features of the Genizer NanoMixer Precision Programmable Control:  Manage flow rates from  0 to 10 mL/min per pump  with an inlet accuracy of ±0.1 mL. This ensures consistent and reproducible results, batch after batch. Flexible Mixing Configurations:  Choose from three models to match your project's needs: the...

  Bringing a nanotechnology product from concept to market is a complex journey. It requires not just individual pieces of equipment, but a fully integrated and compatible ecosystem. At Genizer, we provide exactly that—a comprehensive portfolio of high-performance components and systems designed to work together seamlessly across your entire nano-manufacturing workflow. From research and development to full-scale cGMP production, our products are the building blocks of precision, efficiency, and reliability. Explore the Genizer Ecosystem: The Heart of the Process: Diamond Interaction Chamber Experience unparalleled performance with our patented chamber technology. It’s the core of our homogenizers, engineered for superior particle size reduction and longevity, ensuring your process runs at its peak. The Driving Force: High Pressure Homogenizers & Pumps Our range of homogenizers and sanitary high-pressure pumps deliver the powerful, stable, and controllable pressure required to...

  Creating effective and stable liquid formulations requires a uniform dispersion of active ingredients. Homogenization is a key technique used to achieve this consistency, and selecting the right homogenizer is critical to ensuring product quality and performance. In this article, we’ll walk through the key factors to consider when choosing a homogenizer that fits your specific application needs. Understanding Your Product’s Physical Properties The first step in selecting a homogenizer is to evaluate your product’s characteristics. Consider its viscosity, particle size, and the pressure required for processing. Higher viscosity products generally require greater pressure to break down particles effectively. Similarly, smaller particle sizes often demand higher pressure to achieve a uniform dispersion. The required operating pressure will ultimately depend on the specific properties of your formulation—some products need high-pressure treatment for optimal results, while others per...

  One of Genizer’s most compact pieces of equipment is the HandExtruder . The HandExtruder is popular in academic and small labs because of its small size and low dead volume. Researchers utilize it to get the desired size of liposome or lipid nanoparticle. Particle size can impact circulation time, uptake and stability. All of these are important aspects in different uses for liposomes. The affordability of the HandExtruder makes it an accessible entry point to liposome extrusion for academics. The HandExtruder has been cited in academic work in pharmaceutical research. One example is a study where our Handextruder, with 200nm membranes, was used to create liposomes to study cancer treatment ( link ). In another study, the HandExtruder was used in the preparation of vaccination nanoparticles ( link ). Beyond pharmaceuticals, reasearchers use the HandExtruder in diverse fields like agriculture ( link ), and protocell research ( link ). As time has gone on, we continue to learn from...