Ease of Use and the Genizer Liposome HandExtruder
One of Genizer’s most compact pieces of equipment is the HandExtruder . The HandExtruder is popular in academic and small labs because of its small size and low dead volume. Researchers utilize it to get the desired size of liposome or lipid nanoparticle. Particle size can impact circulation time, uptake and stability. All of these are important aspects in different uses for liposomes. The affordability of the HandExtruder makes it an accessible entry point to liposome extrusion for academics. The HandExtruder has been cited in academic work in pharmaceutical research. One example is a study where our Handextruder, with 200nm membranes, was used to create liposomes to study cancer treatment ( link ). In another study, the HandExtruder was used in the preparation of vaccination nanoparticles ( link ). Beyond pharmaceuticals, reasearchers use the HandExtruder in diverse fields like agriculture ( link ), and protocell research ( link ). As time has gone on, we continue to learn from...