Genizer NanoTechnology

  Title:   Nanoemulsion Breakthroughs: How Genizer’s Homogenizers Solve Stability & Scalability Challenges Subtitle: Achieve sub-100 nm emulsions for pharma, cosmetics, and food applications with high-pressure homogenization technology Why Nanoemulsions Are Transforming Industries Nanoemulsions (20-200 nm droplets) unlock unprecedented potential across sectors: Pharma : Enhanced bioavailability of poorly soluble drugs. Cosmetics : Deeper skin penetration of actives (vitamins, antioxidants). Food & Beverage : Transparent nutrient fortification, improved flavor delivery. Yet, industrial-scale production faces hurdles:  inconsistent particle size ,  physical instability , and  inefficient scaling . Genizer’s High-Pressure Homogenization: Precision Nanoemulsion Engineering Genizer’s microfluidizer-type homogenizers overcome these barriers with cutting-edge HPH technology. Our solutions deliver: 1. Ultra-Fine & Monodisperse Droplets Consistently...

 Escherichia coli is a bacterium that most of us know first from recalls of foods like meat and lettuce. Although E. coli is a commensal (non-harmful) gut bacterium, the wrong circumstance and strain can make infection uncomfortable and dangerous. E. coli is gram negative, meaning it has a double-layered cell membrane that makes it more difficult to treat with antibiotics. Our homogenization equipment is regularly used to disrupt E. coli. In “Identification and Biosynthesis of pro-inflammatory sulfonolipids” authors Hou et al. use the NanoGenizer to break apart E. coli after using it for protein expression. Many other researchers have done the same (https://www.genizer.com/u_file/2206/file/6bffa6a456.pdf, https://www.genizer.com/u_file/2312/file/298f8a65e6.pdf , https://www.genizer.com/u_file/2312/file/3ca3c35d8a.pdf) What makes this common cause of diarrheal illnesses a welcome tool in so many research labs? First, we need to understand the research problem E. coli is being used...

  At Genizer, we want our equipment to be with you every step of the way! That’s why we make equipment that squeezes into an academic lab all the way up to manufacturing. Here’s the   High-Pressure Homogenization  equipment that can take you all the way to capacity. HandGenizer For a more portable solution to high-pressure homogenization, we have the HandGenizer. Well suited to long-term storage, the HandGenizer is great in an academic R&D context. Its’ distinctive manual option and compact size set the HandGenizer apart, though it is best suited to small, even solutions like nanoemulsions. NanoGenizer Next is the NanoGenizer. Our most popular model, the NanoGenizer fits easily in a benchtop with a length under 28 inches (70 cm). The Nanogenizer has a max flow of 100mL/min, and a max pressure of 45,000 psi. Ideal for R&D, laboratory, and small-scale production. The NanoGenizer is quiet and easy to use. It also comes in Dual and Quad options for additional capacity...

 Instrument: Genizer Liposome Extruders AKA: Exosomes Extruders, Artificial Cell Membrane Extruders; Liposomes Preparation devices by extrusion Advantages: Liposome extruders are mainly used for the liposome formulation and achieving uniform size distributions. It is an ideal instrument to generate nanoscale liposome formulations, and to prepare exosomes and artificial cell membranes. By utilizing the tracked-etched filter membranes, the liposome extruders are capable of capturing large particles, precipitation and achieving sterile filtration. Application: Research and Development for the liposomal drug delivery system, vaccine, gene delivery, and cosmetics Working Principles: A liposome is a spherical-shaped vesicle composed of phospholipid bilayers. Phospholipid bilayers are critical components of cell membranes, with hydrophilic and hydrophobic properties. In an aqueous solution, the hydrophobic ends tend to bind to each other, and spontaneously form small sphericalliposomes. T...

  NanoGenizer High Pressure Homogenizer for Nanomaterials NanoGenizer , a lab-scale microfluidic high pressure homogenizer, offers effective performance on particle size reduction and cell disruption. It utilizes interaction high-pressure microfluidic jet technology, and equipped with highly modular power and processing units. NanoGenizer is suitable for rare and valuable samples because of its minimum dead volume design and its continuous flow rate, which enables it to process up to 120 mL/min. With successful applications in various nanotechnology settings, the NanoGenizer has gained increasing recognition due to its notable shear rate, excellent repeatability, and guaranteed scalability.   NanoGenizer provides efficient solutions for various nanomaterials, including: liposomes, nano-emulsions, nano-crystals, micelles, lipid nanoparticles, cosmetic nano-encapsulation materials, nano-particle dispersion, graphene, carbon nanotube, and more. As more organizations recognize thi...

 From Citrus Peels to Diabetes Treatment - Genizer in the Research From Citrus Peels to Diabetes Treatment - Genizer in the Research Type 2 Diabetes is growing as the world’s population ages. This makes treatment more important than ever. Genizer’s clients at the University of Pretoria in South Africa researched improvements to Type 2 Diabetes treatment. Carbohydrates are delicious sugars found in breads, fruits and more. The body breaks carbohydrates down into simple sugars. Next, the insulin hormone converts these sugars to energy or storage. People with diabetes have issues related to insulin. They need help to manage the sugar levels in their blood and prevent hyperglycemia. Without treatment, hyperglycemia can cause negative impacts including death. If you or someone you know has diabetes, you may have seen them use insulin to manage their blood sugar levels. However, you may be less familiar with other treatment options like acarbose. Acarbose prevents amylolytic enzymes from...